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1

Buccal delivery of an α2-adrenergic receptor antagonist, atipamezole, in humans*

Huupponen, Risto, Karhuvaara, Sakari, Anttila, Markku, Vuorilehto, Lauri, Scheinin, Harry

Journal:

Clinical Pharmacology & Therapeutics

Year:

1995

Language:

english

File:

PDF, 544 KB

english, 1995

2

Influence of hydroxychloroquine on the bioavailability of oral metoprolol

Mika Somer, Jaana Kallio, Ullamari Pesonen, Kaija Pyykkö, Risto Huupponen, Mika Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

2000

Language:

english

File:

PDF, 88 KB

english, 2000

3

Effect of Subchronic Metformin Treatment on Macronutrient Selection in Genetically Obese Zucker Rats

Juha Rouru, Risto Huupponen, Eriika Santti, Markku Koulu

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1993

Language:

english

File:

PDF, 363 KB

english, 1993

4

Nurse students' medication competence — An integrative review of the associated factors

Virpi Sulosaari, Satu Kajander, Maija Hupli, Risto Huupponen, Helena Leino-Kilpi

Journal:

Nurse Education Today

Year:

2012

Language:

english

File:

PDF, 870 KB

english, 2012

5

Effects of Diet and Simvastatin on Serum Lipids, Insulin, and Antioxidants in Hypercholesterolemic Men

Jula, Antti, Marniemi, Jukka, Huupponen, Risto, Virtanen, Arja, Rastas, Merja, Rönnemaa, Tapani

Journal:

JAMA The Journal of the American Medical Association

Year:

2002

Language:

english

File:

PDF, 133 KB

english, 2002

6

Effect of the Benzodiazepine Derivative, Diazepam, on the Clonidine-Stimulated Human Growth Hormone Secretion

Koulu, Markku, Pihlajamaki, Kalevi, Huupponen, Risto

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

1983

Language:

english

File:

PDF, 318 KB

english, 1983

7

The single dose pharmacokinetics and safety of deramciclane in healthy male volunteers

Harri Kanerva, Olavi Kilkku, Esa Heinonen, Antti Helminen, Juha Rouru, Simo Tarpila, Mika Scheinin, Risto Huupponen, Imre Klebovich, Sandor Drabant, Arto Urtti

Journal:

Biopharmaceutics & Drug Disposition

Year:

1999

Language:

english

File:

PDF, 201 KB

english, 1999

8

Pharmacokinetics of finrozole (MPV-2213ad), a novel selective aromatase inhibitor, in healthy men

Outi Ahokoski, Kerttu Irjala, Mikko Taalikka, Pekka Manninen, Kaija Halonen, Lauri Kangas, Eeva Salminen, Risto Huupponen, Harry Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

2001

Language:

english

File:

PDF, 71 KB

english, 2001

9

Hormonal effects of MPV-2213ad, a new selective aromatase inhibitor, in healthy male subjects. A phase I study

Outi Ahokoski, Kerttu Irjala, Risto Huupponen, Kaija Halonen, Eeva Salminen, Harry Scheinin

Journal:

British Journal of Clinical Pharmacology

Year:

1998

Language:

english

File:

PDF, 84 KB

english, 1998

10

Dose linearity study of selegiline pharmacokinetics after oral administration: evidence for strong drug interaction with female sex steroids

Kari Laine, Markku Anttila, Antti Helminen, Hari Karnani, Risto Huupponen

Journal:

British Journal of Clinical Pharmacology

Year:

1999

Language:

english

File:

PDF, 99 KB

english, 1999

11

Severe hyponatremia caused by intranasal desmopressin for nocturnal enuresis

Jaana Kallio, Päivi Rautava, Risto Huupponen, Heikki Korvenranta

Journal:

Pediatric Nephrology

Year:

1994

Language:

english

File:

PDF, 143 KB

english, 1994

12

Heavy users of non-steroidal anti-inflammatory drugs: a nationwide prescription database study in Finland

Arja Helin-Salmivaara, Timo Klaukka, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 235 KB

english, 2003

13

Effect of the novel anxiolytic drug deramciclane on the pharmacokinetics and pharmacodynamics of the CYP3A4 probe drug buspirone

Kari Laine, Outi Ahokoski, Risto Huupponen, Jutta Hänninen, Sanna Palovaara, Jori Ruuskanen, Harry Björklund, Markku Anttila, Juha Rouru

Journal:

European Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 222 KB

english, 2003

14

Frequent prescribing of drugs with potential gastrointestinal toxicity among continuous users of non-steroidal anti-inflammatory drugs

Arja Helin-Salmivaara, Risto Huupponen, Arja Virtanen, Jari Lammela, Timo Klaukka

Journal:

European Journal of Clinical Pharmacology

Year:

2005

Language:

english

File:

PDF, 254 KB

english, 2005

15

Risk of serious upper gastrointestinal events with concurrent use of NSAIDs and SSRIs: a case-control study in the general population

Arja Helin-Salmivaara, Teppo Huttunen, Juha M. Grönroos, Timo Klaukka, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 117 KB

english, 2007

16

Reply to letter by Foster, van der Molen and de Jong-van den Berg

Pasi Lampela, Sirpa Hartikainen, Raimo Sulkava, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 44 KB

english, 2007

17

Selective prescribing of simvastatin and atorvastatin by patient characteristics at treatment initiation over a 7-year period in Finland

Heli Halava, Arja Helin-Salmivaara, Jouni Junnila, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 132 KB

english, 2009

18

Protopathic bias in observational studies on statin effectiveness

Maarit Jaana Korhonen, Risto Huupponen, Päivi Ruokoniemi, Arja Helin-Salmivaara

Journal:

European Journal of Clinical Pharmacology

Year:

2009

Language:

english

File:

PDF, 64 KB

english, 2009

19

Dynamics of long-term statin therapy

Maarit Jaana Korhonen, Arja Helin-Salmivaara, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 228 KB

english, 2011

20

Suboptimal use of statins at treatment initiation

Vesa Kiviniemi, Piia Peura, Arja Helin-Salmivaara, Jaana E. Martikainen, Juha Hartikainen, Risto Huupponen, Maarit Jaana Korhonen

Journal:

European Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 72 KB

english, 2011

21

Shift of statin use towards the elderly in 1995−2005: a nation-wide register study in Finland

Päivi Ruokoniemi, Arja Helin-Salmivaara, Timo Klaukka, Pertti J. Neuvonen, Risto Huupponen

Journal:

British Journal of Clinical Pharmacology

Year:

2008

Language:

english

File:

PDF, 561 KB

english, 2008

22

Statin adherence and the risk of major coronary events in patients with diabetes: a nested case–control study

Päivi Ruokoniemi, Maarit J. Korhonen, Arja Helin-Salmivaara, Piia Lavikainen, Antti Jula, Seppo Y. T. Junnila, Raimo Kettunen, Risto Huupponen

Journal:

British Journal of Clinical Pharmacology

Year:

2011

Language:

english

File:

PDF, 893 KB

english, 2011

23

Heart rate variability is independently associated with C-reactive protein but not with Serum amyloid A. The Cardiovascular Risk in Young Finns Study

Atte Haarala, Mika Kähönen, Carita Eklund, Juulia Jylhävä, Tuomas Koskinen, Leena Taittonen, Risto Huupponen, Terho Lehtimäki, Jorma Viikari, Olli T. Raitakari, Mikko Hurme

Journal:

European Journal of Clinical Investigation

Year:

2011

Language:

english

File:

PDF, 84 KB

english, 2011

24

Systemic absorption of topically applied ocular atropine

Lahdes, Kimmo, Kaila, Timo, Huupponen, Risto, Salminen, Lotta, Iisalo, Esko

Journal:

Clinical Pharmacology & Therapeutics

Year:

1988

Language:

english

File:

PDF, 317 KB

english, 1988

25

High Serum Leptin Is Associated with Attenuated Coronary Vasoreactivity

Dr. Jan Sundell, Risto Huupponen, Olli T. Raitakari, Pirjo Nuutila, Juhani Knuuti

Journal:

Year:

2003

Language:

english

File:

PDF, 58 KB

english, 2003

26

Adverse drug effects in elderly people – a disparity between clinical examination and adverse effects self-reported by the patient

Pasi Lampela, Sirpa Hartikainen, Raimo Sulkava, Risto Huupponen

Journal:

European Journal of Clinical Pharmacology

Year:

2007

Language:

english

File:

PDF, 120 KB

english, 2007

27

Metformin and brown adipose tissue thermogenetic activity in genetically obese Zucker rats

Juha Rouru, Kaisa Isaksson, Eriika Santti, Risto Huupponen, Markku Koulu

Journal:

European Journal of Pharmacology: Molecular Pharmacology

Year:

1993

Language:

english

File:

PDF, 457 KB

english, 1993

28

Cardiac positron emission tomography imaging with [11c]hydroxyephedrine, a specific tracer for sympathetic nerve endings, and its functional correlates in congestive heart failure

Risto K Vesalainen, Mikko Pietilä, Kari U.O Tahvanainen, Tuomas Jartti, Mika Teräs, Kjell Någren, Pertti Lehikoinen, Risto Huupponen, Heikki Ukkonen, Markku Saraste, Juhani Knuuti, Liisa-Maria Voipio-

Journal:

The American Journal of Cardiology

Year:

1999

Language:

english

File:

PDF, 364 KB

english, 1999

29

Effects of Chronic Celiprolol Treatment on Brown Fat, Feeding, and Drinking in fa/fa Zucker Rats

Eriika Savontaus, Juha Rouru, Kimmo Malminiemi, Virve Luukkaa, Ullamari Pesonen, Markku Koulu, Risto Huupponen

Journal:

Pharmacology Biochemistry and Behavior

Year:

2000

Language:

english

File:

PDF, 131 KB

english, 2000

30

Prostaglandin F2α Binding to Bovine Ocular and Synthetic Melanins in Vitro

Pirjo Aula, Timo Kaila, Risto Huupponen, Lotta Salminen, Esko Iisalo

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1989

Language:

english

File:

PDF, 304 KB

english, 1989

31

Effect of Chronic Treatment with ICI D7114, a Selective β3-Adrenoceptor Agonist, on Macronutrient Selection and Brown Adipose Tissue Thermogenesis in Sprague-Dawley Rats

Eriika Santti, Taina Rouvari, Juha Rouru, Risto Huupponen, Markku Koulu

Journal:

Basic & Clinical Pharmacology & Toxicology

Year:

1994

Language:

english

File:

PDF, 375 KB

english, 1994

32

Transient corneal anaesthesia after topical pindolol in rabbits

Risto Huupponen, Lotta Salminen

Journal:

Acta Ophthalmologica (Blackwell)

Year:

1985

Language:

english

File:

PDF, 256 KB

english, 1985

33

The effect of ocular pigmentation on intraocular pressure responce to timolol

Lotta Salminen, György Imre, Risto Huupponen

Journal:

Acta Ophthalmologica (Blackwell)

Year:

1985

Language:

english

File:

PDF, 241 KB

english, 1985

34

The pharmacokinetics of ocularly applied timolol in rabbits

Risto Huupponen, Timo Kaila, Lotta Salminen, Arto Urtti

Journal:

Acta Ophthalmologica (Blackwell)

Year:

1987

Language:

english

File:

PDF, 248 KB

english, 1987

35

Differential Regulation of Uncoupling Proteins by Chronic Treatments with β3-Adrenergic Agonist BRL 35135 and Metformin in Obesefa/faZucker Rats

Eriika Savontaus, Juha Rouru, Olivier Boss, Risto Huupponen, Markku Koulu

Journal:

Biochemical and Biophysical Research Communications

Year:

1998

Language:

english

File:

PDF, 135 KB

english, 1998

36

Effect of chronic treatment with TFMPP, a 5-HT1 receptor agonist, on food intake, weight gain, plasma insulin and neuropeptide mRNA expression in obese Zucker rats

Juha Rouru, Ullamari Pesonen, Kaisa Isaksson, Risto Huupponen, Markku Koulu

Journal:

European Journal of Pharmacology

Year:

1993

Language:

english

File:

PDF, 832 KB

english, 1993

37

Anorectic effect of metformin in obese Zucker rats: lack of evidence for the involvement of neuropeptide Y

Juha Rouru, Ullamari Pesonen, Markku Koulu, Risto Huupponen, Eriika Santti, Kirsi Virtanen, Taina Rouvari, Meena Jhanwar-Uniyal

Journal:

European Journal of Pharmacology

Year:

1995

Language:

english

File:

PDF, 807 KB

english, 1995

38

Persistence with statin therapy in diabetic and non-diabetic persons: a nation-wide register study in 1995-2005 in Finland

Arja Helin-Salmivaara, Piia Lavikainen, Päivi Ruokoniemi, Maarit Korhonen, Risto Huupponen

Journal:

Diabetes Research and Clinical Practice

Year:

2009

Language:

english

File:

PDF, 198 KB

english, 2009

39

In Vivo Detection of Vascular Adhesion Protein-1 in Experimental Inflammation

Kimmo Jaakkola, Tuomo Nikula, Riikka Holopainen, Tommi Vähäsilta, Marja-Terttu Matikainen, Marja-Leena Laukkanen, Risto Huupponen, Lauri Halkola, Lauri Nieminen, Jukka Hiltunen, Sakari Parviainen, Mic

Journal:

The American Journal of Pathology

Year:

2000

Language:

english

File:

PDF, 1.29 MB

english, 2000

40

Insulin resistance of human adipose tissue in obesity measured with [18F]FDG and PET

Kirsi A Virtanen, Pauliina Peltoniemi, Päivi Marjamäki, Markku Asola, Riitta Parkkola, Risto Huupponen, Peter Lönnroth, Tapani Rönnemaa, Juhani Knuuti, Pirjo Nuutila

Journal:

Diabetes Research and Clinical Practice

Year:

2000

Language:

english

File:

PDF, 143 KB

english, 2000

41

Focusing on changing clinical practice to enhance rational prescribing—collaboration and networking enable comprehensive approaches

Arja Helin-Salmivaara, Risto Huupponen, Timo Klaukka, Kalle Hoppu

Journal:

Year:

2003

Language:

english

File:

PDF, 231 KB

english, 2003

42

Potentiation of the anti-obesity effect of the selective β3-adrenoceptor agonist BRL 35135 in obese Zucker rats by exercise

Eriika Santti, Risto Huupponen, Juha Rouru, Virve Hanninen, Ullamari Pesonen, Meena Jhanwar-Uniyal, Markku Koulu

Journal:

British Journal of Pharmacology

Year:

1994

Language:

english

File:

PDF, 1.31 MB

english, 1994

43

Subchronic treatment with metformin produces anorectic effect and reduces hyperinsulinemia in genetically obese zucker rats

Juha Rouru, Risto Huupponen, Ullamari Pesonen, Markku Koulu

Journal:

Year:

1992

Language:

english

File:

PDF, 460 KB

english, 1992

44

A longitudinal analysis on associations of adiponectin levels with metabolic syndrome and carotid artery intima-media thickness. The Cardiovascular Risk in Young Finns Study

Markus Juonala, Liisa A. Saarikoski, Jorma S.A. Viikari, Mervi Oikonen, Terho Lehtimäki, Leo-Pekka Lyytikäinen, Risto Huupponen, Costan G. Magnussen, Juha Koskinen, Tomi Laitinen, Leena Taittonen, Mik

Journal:

Atherosclerosis

Year:

2011

Language:

english

File:

PDF, 223 KB

english, 2011

45

Plasminogen activator inhitor-1 associates with cardiovascular risk factors in healthy young adults in the Cardiovascular Risk in Young Finns Study

Juho R.H. Raiko, Mervi Oikonen, Maria Wendelin-Saarenhovi, Niina Siitonen, Mika Kähönen, Terho Lehtimäki, Jorma Viikari, Antti Jula, Britt-Marie Loo, Risto Huupponen, Liisa Saarikoski, Markus Juonala,

Journal:

Atherosclerosis

Year:

2012

Language:

english

File:

PDF, 144 KB

english, 2012

46

Low serum adiponectin is associated with high circulating oxidized low-density lipoprotein in patients with type 2 diabetes mellitus and coronary artery disease

Riikka Lautamäki, Tapani Rönnemaa, Risto Huupponen, Terho Lehtimäki, Patricia Iozzo, K.E. Juhani Airaksinen, Juhani Knuuti, Pirjo Nuutila

Journal:

Year:

2007

Language:

english

File:

PDF, 236 KB

english, 2007

47

Chronic treatment with BRL 35135 potentiates the action of insulin on lipid metabolism

Kirsi A Virtanen, Juha Rouru, Virve Hänninen, Eriika Savontaus, Taina Rouvari, Tomi Teirmaa, Markku Koulu, Risto Huupponen

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 165 KB

english, 1997

48

Anti-obesity effect of MPV-1743 A III, a novel imidazoline derivative, in genetic obesity

Eriika Savontaus, Atso Raasmaja, Juha Rouru, Markku Koulu, Ullamari Pesonen, Raimo Virtanen, Juha-Matti Savola, Risto Huupponen

Journal:

European Journal of Pharmacology

Year:

1997

Language:

english

File:

PDF, 115 KB

english, 1997

49

Effects of ZD7114, a selective β3-adrenoceptor agonist, on neuroendocrine mechanisms controlling energy balance

Eriika Savontaus, Ullamari Pesonen, Juha Rouru, Risto Huupponen, Markku Koulu

Journal:

European Journal of Pharmacology

Year:

1998

Language:

english

File:

PDF, 215 KB

english, 1998

50

Frequency and Clinical Relevance of Drug Interactions with Lovastatin and Simvastatin

Tuire Tirkkonen, Anna Ryynänen, Tero Vahlberg, Kerttu Irjala, Timo Klaukka, Risto Huupponen, Kari Laine

Journal:

Year:

2008

Language:

english

File:

PDF, 120 KB

english, 2008

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